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Regulation Of Cystic Fibrosis Transmembrane Regulator Trafficking And Protein Expression By A Rho Family Small Gtpase Tc10
JOURNAL OF BIOLOGICAL CHEMISTRY, no. 5 (2005): 3731-3739
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The cystic fibrosis transmembrane conductance regulator (CFTR)-interacting protein, CFTR-associated ligand (CAL) down-regulates total and cell surface CFTR by targeting CFTR for degradation in the lysosome. Here, we report that a Rho family small GTPase TC10 interacts with CAL. This interaction specifically up-regulates CFTR protein expre...More
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