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Elevated Level of Nuclear Protein Kinase C in Multidrug-resistant MCF-7 Human Breast Carcinoma Cells
Cancer Research, no. 13 (1992)
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Abstract
Previous studies have demonstrated elevated levels of protein kinase C (PKC) activity in multidrug-resistant human breast carcinoma MCF- 7/ADR cells compared to control drug-sensitive MCF-7/WT cells (R. L. Fine, J. Patel, and B. A. Chabner, Proc. Nati. Acad. Sci. USA, 85:582- 586, 1988). In our present studies, immunohistochemical localiz...More
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