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Cardiac Hypertrophy And Impaired Relaxation In Transgenic Mice Overexpressing Triadin 1

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 6 (2001): 4142-4149

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transgenic mice

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Triadin 1 is a major transmembrane protein in cardiac junctional sarcoplasmic reticulum (SR), which forms a quaternary complex with the ryanodine receptor (Ca2+ release channel), junctin, and calsequestrin. To better understand the role of triadin 1 in excitation-contraction coupling in the heart, we generated transgenic mice with targete...More

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