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Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.

The Journal of biological chemistry, no. 43 (2002): 41268-41273

被引用383|浏览10
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Most Ras proteins are posttranslationally modified by a palmitoyl lipid moiety through a thioester linkage. However, the mechanism by which this occurs is not known. Here, evidence is presented that the Ras2 protein of Saccharomyces cerevisiae is palmitoylated by a Ras protein acyltransferase (Ras PAT) encoded by the ERF2 and ERF4 genes. ...更多

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