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Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia.

JOURNAL OF CELL BIOLOGY, no. 3 (2010): 541.0-556

被引用334|浏览6
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Invasive cancer cells are believed to breach the basement membrane (BM) using specialized protrusions called invadopodia. We found that the crossing of a native BM is a three-stage process: invadopodia indeed form and perforate the BM, elongate into mature invadopodia, and then guide the cell toward the stromal compartment. We studied the...更多

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