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C/EBP, c-Myb, and PU.1 cooperate to regulate the neutrophil elastase promoter.
MOLECULAR AND CELLULAR BIOLOGY, no. 9 (1996): 4717-4725
The murine neutrophil elastase (NE) gene is expressed specifically in immature myeloid cells. A 91-bp NE promoter region contains three cis elements which are conserved evolutionarily and are essential for activation of the promoter in differentiating 32D c13 myeloid cells. These elements bound c-Myb (at -49), C/EBP alpha (at -57), and PU...More
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