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Malonyl-coenzyme A reductase in the modified 3-hydroxypropionate cycle for autotrophic carbon fixation in archaeal Metallosphaera and Sulfolobus spp.

JOURNAL OF BACTERIOLOGY, no. 24 (2006): 8551.0-8559.0

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metabolic pathwayrecombinant proteinsn terminalcarbon dioxideescherichia coliMore(4+)

Abstract

Autotrophic members of the Suffolobales (Crenarchaeota) contain acetyl-coenzyme A (CoA)/propionyl-CoA carboxylase as the CO2 fixation enzyme and use a modified 3-hydroxypropionate cycle to assimilate CO, into cell material. In this central metabolic pathway malonyl-CoA, the product of acetyl-CoA carboxylation, is further reduced to 3-hydr...More

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