Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions.
CURRENT OPINION IN CELL BIOLOGY, no. 6.0 (1999): 699-704
One important mechanism for functional innovation during evolution is the duplication of genes and entire genomes. Evidence is accumulating that during the evolution of vertebrates from early deuterostome ancestors entire genomes were duplicated through two rounds of duplications (the one-to-two-to-four' rule). The first genome duplicatio...更多
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