Subunit stoichiometry of human muscle chloride channels.
JOURNAL OF GENERAL PHYSIOLOGY, no. 1 (1997): 93-104
Voltage-gated Cl- channels belonging to the ClC family appear to function as homomultimers, but the number of subunits needed to form a functional channel is controversial. To determine subunit stoichiometry, we constructed dimeric human skeletal muscle Cl- channels in which one subunit was tagged by a mutation (D136G) that causes profoun...更多
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