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The discovery of novel calcium sensing receptor negative allosteric modulators.

Gayatri Balan,Jonathan Bauman,Samit Bhattacharya,Mayda Castrodad,David R Healy,Michael Herr,Paul Humphries,Sandra Jennings,Amit S Kalgutkar,Brendon Kapinos,Vishal Khot,Kimberly Lazarra,Mei Li,Yan Li,Constantin Neagu,Robert Oliver,David W Piotrowski,David Price,Hong Qi,Holly A Simmons,James Southers,Liuqing Wei,Yan Zhang,Vishwas M Paralkar

Bioorganic & Medicinal Chemistry Letters（2009）

引用 39|浏览47
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摘要
The discovery of a structurally novel, orally bioavailable series of calcium sensing receptor negative allosteric modulators is described.
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关键词
Calcium sensing receptor,Negative allosteric modulators,Osteoporosis,Parathyroid hormone
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