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Developing a new paradigm for thymus organogenesis.
NATURE REVIEWS IMMUNOLOGY, no. 4 (2004): 278.0-289
The mature thymic epithelium is complex, with two major compartments-the cortex and the medulla-each containing several functionally distinct epithelial-cell types. There is considerable debate as to the embryonic origins of these different thymic epithelial-cell subpopulations. The textbook view is a dual origin, with cortical thymic epi...More
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