The emerging role of EpCAM in cancer and stem cell signaling.

Cancer research, no. 14 (2009): 5627-5629

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Initially discovered as a dominant antigen on colon carcinomas, the epithelial cell adhesion molecule (EpCAM) was considered a mere cell adhesion molecule and reliable surface-binding site for therapeutic antibodies. Recent findings can better explain the relevance of EpCAM's high-level expression on human cancers and cancer propagating c...更多

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