Mossy fiber sprouting as a potential therapeutic target for epilepsy.

CURRENT NEUROVASCULAR RESEARCH, no. 1 (2013): 3-10

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Hippocampal mossy fibers, axons of dentate granule cells, converge in the dentate hilus and run through a narrow area called the stratum lucidum to synapse with hilar and CA3 neurons. In the hippocampal formation of temporal lobe epilepsy patients, however, this stereotyped pattern of projection is often collapsed; the mossy fibers branch...更多

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