Inner ear biocompatibility of lipid nanocapsules after round window membrane application.
International Journal of Pharmaceutics(2011)
摘要
LNCs did not cause hearing loss, cell death, and changes of synaptophysin, ribbon synapses, and S-100. But a neurofilament decrease was observed in SGC and cochlear nerve.
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关键词
ABR,DAPI,FITC,HE,IHC,LNCs,NF-200,OHC,PBS,RWM,SGCs,SGSCs,SNHL,TRITC
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