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Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro.

JOURNAL OF CLINICAL INVESTIGATION, no. 3 (1996): 698-705

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Bisphosphonates are used with increasing frequency in the management of skeletal complications in patients with breast cancer, In this paper, we have investigated whether bisphosphonates, besides their known beneficial effects on tumor-associated osteoclastic resorption, are capable of inhibiting breast cancer cell adhesion to bone matrix...更多

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