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Involvement of hippocampal AMPA glutamate receptor changes and the cAMP/protein kinase A/CREB-P signalling pathway in memory consolidation of an avoidance task in rats.

BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, no. 8 (1997): 961-965

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pubmed.ncbi.nlm.nih.gov academic.microsoft.com

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glutamate AMPA receptorscAMP/PKA/CREB pathwaymemory formationrat hippocampus

Abstract

Training in step-down inhibitory avoidance (0.3-mA footshock) is followed by biochemical changes in rat hippocampus that strongly suggest an involvement of quantitative changes in glutamate AMPA receptors, followed by changes in the dopamine D-1 receptor/cAMP/protein kinase A (PKA)/CREB-P signalling pathway in memory consolidation. AMPA b...More

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R Bernabeu

M Cammarota

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I Izquierdo

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J H Medina

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