Tolerance To Self Gangliosides Is The Major Factor Restricting The Antibody Response To Lipopolysaccharide Core Oligosaccharides In Campylobacter Jejuni Strains Associated With Guillain-Barre Syndrome

Guillain-Barre syndrome following Campylobacter jejuni infection is frequently associated with anti-ganglioside autoantibodies mediated by molecular mimicry with ganglioside-like oligosaccharides on bacterial lipopolysaccharide (LPS). The regulation of antibody responses to these T-cell-independent antigens is poorly understood, and only ...更多