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Interaction In Vivo And In Vitro Of The Metastasis-Inducing S100 Protein, S100a4 (P9ka) With S100a1

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 15 (2000): 11141-11146

Cited: 88|Views29
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Abstract

The calcium-binding protein S100A4 (p9Ka) has been shown to cause a metastatic phenotype in rodent mammary tumor cells and in transgenic mouse model systems. mRNA for S100A4 (p9Ka) is present at a generally higher level in breast carcinoma than in benign breast tumor specimens, and the presence of immunocytochemically detected S100A4 corr...More

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