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Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

JOURNAL OF CELL BIOLOGY, no. 6 (1996): 1403-1415

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Activated rhoA, a ras-related GTP-binding protein, stimulates the appearance of stress fibers, focal adhesions, and tyrosine phosphorylation in quiescent cells (Ridley, A.J., and A. Hall, 1992. Cell. 70:389-399). The pathway by which rho triggers these events has not been elucidated. Many of the agents that activate rho (e.g., vasopressin...更多

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