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Overexpression of OATP1B3 confers apoptotic resistance in colon cancer.

Cancer research, no. 24 (2008): 10315-10323

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Organic anion transporting polypeptide 1B3 (OATP1B3, SLCO1B3) is normally expressed in hepatocytes. In this study, we showed frequent overexpression of OATP1B3 in colorectal adenocarcinomas. Quantitative reverse transcription-PCR analysis of 17 colon tumors indicated tumoral overexpression of OATP1B3 by approximately 100-fold, compared wi...更多

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