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DNA fragment sizing by single molecule detection in submicrometer-sized closed fluidic channels.

ANALYTICAL CHEMISTRY, no. 6 (2002): 1415-1422

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The fabrication of fluidic channels with dimensions smaller than I mum is described and characterized in respect to their use for detection of individual DNA molecules. The sacrificial layer technique is used to fabricate these devices as it provides CMOS-compatible materials exhibiting low fluorescence background. It also allows creating...更多

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