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Histone H4-Lysine 20 Monomethylation Is Increased In Promoter And Coding Regions Of Active Genes And Correlates With Hyperacetylation

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 46 (2005): 38814-38822

Cited: 111|Views25
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Abstract

Methylation and acetylation of position-specific lysine residues in the N-terminal tail of histones H3 and H4 play an important role in regulating chromatin structure and function. In the case of H3-Lys(4), H3-Lys(9), H3-Lys(27), and H4-Lys(20), the degree of methylation was variable from the mono- to the di- or trimethylated state, each ...More

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