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Infectious Viral Dna Of Murine Leukemia-Virus

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, no. 12 (1975): 4910-4913

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pubmed.ncbi.nlm.nih.gov academic.microsoft.com

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kineticsvirus replicationcalcium phosphatebiochemistrymetabolismMore(3+)

Abstract

A fraction of the unintegrated viral DNA that appears early after infection of mouse cells by Moloney leukemia virus is infectious. The infectivity could be deomonstrated by an XC plaque assay of the cells exposed to DNA co-precipitated with calcium phosphate. The number of plaques deriving from closed-circular, supercoiled DNA was propor...More

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