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Pax6 Is Required For The Normal Development Of The Forebrain Axonal Connections

DEVELOPMENT, no. 21 (2002): 5041-5052

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The transcription factor PAX6 has been implicated in forebrain patterning, cerebral cortical arealization and in development of thalamocortical connections. Using a Pax6/lacZ knockout mouse, in which the endogenous Pax6 expression is reflected by beta-galactosidase activity, we have studied the consequences of the loss of Pax6 function on...更多

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