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Genetic drift can dominate short-term human immunodeficiency virus type 1 nef quasispecies evolution in vivo.

JOURNAL OF VIROLOGY, no. 6 (1997): 4233-4240

Cited: 58|Views25
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Abstract

The evolution of human immunodeficiency virus (HIV) type 1 nef quasispecies in a patient clonally infected with a contaminated batch of blood clotting factor IX was monitored. nef sequences were derived at 11, 25, and 41 months postinfection from infected peripheral blood mononuclear cells after molecular cloning of PCR-amplified proviral...More

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