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Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

GUT, no. 1.0 (2009): 41-48

Cited: 130|Views24
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Abstract

Background: Defects in the small intestinal epithelial barrier have been associated with inflammatory bowel disease but their role in the causation of disease is still a matter of debate. In some models of disease increased permeability appears to be a very early event. The interleukin 10 (IL10) gene-deficient mouse spontaneously develops...More

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