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Surfactant proteins A and D inhibit the growth of Gram-negative bacteria by increasing membrane permeability.
JOURNAL OF CLINICAL INVESTIGATION, no. 10 (2003): 1589-1602
The pulmonary collectins, surfactant proteins A (SP-A) and D (SP-D), have been reported to bind lipopolysaccharide (LPS), opsonize microorganisms, and enhance the clearance of lung pathogens. In this study, we examined the effect of SP-A and SP-D on the growth and viability of Gram-negative bacteria. The pulmonary clearance of Escherichia...More
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