Requirement For Multiple Domains Of The Protein Arginine Methyltransferase Carm1 In Its Transcriptional Coactivator Function

The p160 coactivator complex plays a critical role in transcriptional activation by nuclear receptors and possibly other classes of DNA-binding transcriptional activators. The complex contains at least one of three p160 coactivators (SRC-1, GRIP1/TIF2, or pCIP/RAC3/ACTR/ AIB1/TRAM1), a histone acetyltransferase such as CBP or p300, and th...更多