2-(8-Hydroxy-6-Methoxy-1-Oxo-1h-2-Benzopyran-3-Yl) Propionic Acid, An Inhibitor Of Angiogenesis, Ameliorates Renal Alterations In Obese Type 2 Diabetic Mice

One of the mechanisms involved in the progression of diabetic nephropathy, the most common cause of end-stage renal failure, is angiogenic phenomenon associated with the increase of angiogenic factors such as vascular endothelial growth factor (VEGF)-A and angiopoietin (Ang)-2, an antagonist of Ang-1. In the present study, we examined the...更多