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Cytoplasmic Dynein and LIS1 Are Required for Microtubule Advance during Growth Cone Remodeling and Fast Axonal Outgrowth

JOURNAL OF NEUROSCIENCE, no. 21 (2007): 5823-5834

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growth conedyneinLIS1microtubuleaxonMore(1+)

Abstract

Recent evidence has implicated dynein and its regulatory factors dynactin and LIS1 in neuronal and non-neuronal cell migration. In the current study we sought to test whether effects on neuronal cell motility might reflect, in part, a role for these proteins in the growth cone. In chick sensory neurons subjected to acute laminin treatment...More

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P. W. Grabham

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G. E. Seale

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M. Bennecib

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D. J. Goldberg

R. B. Vallee

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