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Immune evasion by murine melanoma mediated through CC chemokine receptor-10.

JOURNAL OF EXPERIMENTAL MEDICINE, no. 9 (2003): 1337-1347

Cited: 144|Views48

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pubmed.ncbi.nlm.nih.gov academic.microsoft.com

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metastasischemokine receptorcancercell signaling

Abstract

Human melanoma cells frequently express CC chemokine receptor (CCR)10, a receptor whose ligand (CCL27) is constitutively produced by keratinocytes. Compared with B16 murine melanoma, cells rendered more immunogenic via overexpression of luciferase, B16 cells that overexpressed both luciferase and CCR10 resisted host immune responses and r...More

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