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Regulation of the endocycle/gene amplification switch by Notch and ecdysone signaling.
JOURNAL OF CELL BIOLOGY, no. 5 (2008): 885-896
T he developmental signals that regulate the switch from genome-wide DNA replication to site-specific amplification remain largely unknown. Drosophila melanogaster epithelial follicle cells, which begin synchronized chorion gene amplification after three rounds of endocycle, provide an excellent model for study of the endocycle/gene ampli...More
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