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Expression patterns and prognostic value of Bag-1 and Bcl-2 in breast cancer.

Breast cancer research : BCR, no. 2 (2008): R35-R35

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Bcl-2 antanogene-1 (Bag-1) binds the anti-apoptotic mediator Bcl-2, and enhances its activity. Bcl-2 and Bag-1 are associated with chemotherapy resistance in cancer cells. Drugs that target Bcl-2 are currently in clinical development. The purpose of the present study was to examine expression patterns of Bag-1 in a large cohort of breast ...更多

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