Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Cell, no. 4 (2006): 663-676
Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about factors that induce this reprogramming. Here, we demonstrate induction of pluripotent stem cells from mouse embryonic or adult fibroblasts by introducing four f...更多
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