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Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development.

Proceedings of the National Academy of Sciences of the United States of America, no. 5 (1997): 1852-1856

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Type III collagen is a fibrillar forming collagen comprising three alpha1(III) chains and is expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin. Mutations in the COL3A1 gene have been implicated as a cause of typ...更多

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