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Dynamic scaffolding in a G protein-coupled signaling system.

Cell, no. 1 (2007): 80-92

Cited: 96|Views34
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Abstract

The INAD scaffold organizes a multiprotein complex that is essential for proper visual signaling in Drosophila photoreceptor cells. Here we show that one of the INAD PDZ domains (PDZ5) exists in a redox-dependent equilibrium between two conformations—a reduced form that is similar to the structure of other PDZ domains, and an oxidized for...More

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