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Zinc availability regulates exit from meiosis in maturing mammalian oocytes

Nature Chemical Biology, no. 9 (2010): 674-681

Cited: 144|Views25
WOS NATURE

Abstract

Cellular metal ion fluxes are known in alkali and alkaline earth metals but are not well documented in transition metals. Here we describe major changes in the zinc physiology of the mammalian oocyte as it matures and initiates embryonic development. Single-cell elemental analysis of mouse oocytes by synchrotron-based X-ray fluorescence m...More

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