Conserved regulation of MAP kinase expression by PUF RNA-binding proteins.
PLOS GENETICS, no. 12 (2007): 2540.0-2550.0
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摘要
control many cellular processes critical for animal development and tissue homeostasis. In the present work, we report that PUF proteins act directly on MAPK/ERK-encoding mRNAs to downregulate their expression in both the Caenorhabditis elegans germline and human embryonic stem cells. In C. elegans, FBF/PUF binds regulatory elements in th...更多
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