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Activation Of P90 Ribosomal S6 Kinase By Orf45 Of Kaposi'S Sarcoma-Associated Herpesvirus And Its Role In Viral Lytic Replication

JOURNAL OF VIROLOGY, no. 4 (2008): 1838-1850

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The extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase (MAPK) pathway is essential for infection by a variety of viruses. The p90 ribosomal S6 kinases (RSKs) are direct substrates of ERK and functional mediators of ERK MAPK signaling, but their roles in viral infection have never been examined. We demonstrate tha...更多

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