VE-cadherin and claudin-5: it takes two to tango.
NATURE CELL BIOLOGY, no. 8 (2008): 883.0-885
Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively. Emerging evidence suggests that VE-cadherin controls claudin-5 expression by preventing the nuclear accumulation of FoxO1 and -catenin, which repress the claudin-5 pr...更多
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