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Accelerated Protein Evolution And Origins Of Human-Specific Features: Foxp2 As An Example

GENETICS, no. 4 (2002): 1825-1835

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Genes responsible for human-specific phenotypes may have been under altered selective pressures in human evolution and thus exhibit changes in substitution rate and pattern at the protein sequence level. Using comparative analysis of human, chimpanzee, and mouse protein sequences, we identified two genes (PRM2 and FOXP2) with significantl...更多

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