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FLASH: fast length adjustment of short reads to improve genome assemblies.

BIOINFORMATICS, no. 21 (2011): 2957-2963

引用2583|浏览27
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Motivation: Next-generation sequencing technologies generate very large numbers of short reads. Even with very deep genome coverage, short read lengths cause problems in de novo assemblies. The use of paired-end libraries with a fragment size shorter than twice the read length provides an opportunity to generate much longer reads by overl...更多

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