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Transition-Metal-Free Sonogashira-Type Coupling Reactions in Water
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, no. 24 (2004): 4713-4716
摘要
Microwave-assisted transition-metal-free Sonogashira-type coupling reactions are described. The reactions are run in water as the sole solvent, without the need for copper(I) or any transition-metal-phosphane complex. The scope of the methodology was tested by reaction of a wide variety of aryl halides and heteroaryl halides. The reaction...更多
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