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Cdk1 negatively regulates midzone localization of the mitotic kinesin Mklp2 and the chromosomal passenger complex.

Current Biology, no. 7 (2009): 607-612

Cited: 115|Views24
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Abstract

The survival of eukaryotes depends on the accurate coordination of mitosis with cytokinesis. Key for the coordination of both processes is the chromosomal passenger complex (CPC) comprising Aurora-B, INCENP, survivin, and borealin 1, 2, 3, 4, 5. The translocation of the CPC from centromeres to the spindle midzone, a structure composed of ...More

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