'Edgetic' perturbation of a C. elegans BCL2 ortholog.
NATURE METHODS, no. 11 (2009): 843-U89
Genes and gene products do not function in isolation but within highly interconnected 'interactome' networks, modeled as graphs of nodes and edges representing macromolecules and interactions between them, respectively. We propose to investigate genotype-phenotype associations by methodical use of alleles that lack single interactions, wh...更多
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