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Towards In Vivo Application Of Rna Interference - New Toys, Old Problems

ARTHRITIS RESEARCH & THERAPY, no. 2 (2004): 78-85

Cited: 62|Views23

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pubmed.ncbi.nlm.nih.gov academic.microsoft.com

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functional genomics gene silencing primary mammalian cell small interfering RNA transfection

Abstract

RNA interference (RNAi) is the sequence-specific degradation of mRNA by short double-stranded RNA molecules. The technology, introduced only 5 years ago, has stimulated many fantasies regarding the future of functional gene analysis and gene therapy. Given its ease of application, its high efficiency and remarkable specificity, RNAi holds...More

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Sascha Rutz

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Alexander Scheffold

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