Combining MCMC with 'sequential' PKPD modelling.
Journal of pharmacokinetics and pharmacodynamics, no. 1 (2009): 19-38
We introduce a method for preventing unwanted feedback in Bayesian PKPD link models. We illustrate the approach using a simple example on a single individual, and subsequently demonstrate the ease with which it can be applied to more general settings. In particular, we look at the three 'sequential' population PKPD models examined by Zhan...更多
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