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Coagulation Facilitates Tumor Cell Spreading In The Pulmonary Vasculature During Early Metastatic Colony Formation

CANCER RESEARCH, no. 23 (2004): 8613-8619

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Coagulation has long been known to facilitate metastasis. To pinpoint the steps where coagulation might play a role in the metastasis, we used three-dimensional visualization of direct infusion of fluorescence labeled antibody to observe the interaction of tumor cells with platelets and fibrinogen in isolated lung preparations. Tumor cell...更多

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