Detection of causes of iron deficiency anemia by ~(18)F-FDG SPECT with coincidence image

Objective To study the value of 18F-fluorodeoxyglucose(18 F-FDG) SPECT with coincidence image in detection of malignant causes of iron deficiency anemia.Methods 18 F-FDG SPECT image was carried out in 53 patients with iron deficiency anemia.Transaxial,coronal and sagittal section image of the body were reconstructed by computer based on X-ray scan 45 min after intravenous injection of 18F-FDG 5～8 mCi.Results In 53 patients,31 cases of iron deficiency anemia were caused by gastroenteric malignancies and 22 cases by non-malignant diseases.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of 18 F-FDG SPECT image were 90.3%(28/31), 81.8%(18/22),86.8%(46/53),87.5%(28/32) and 85.7%(18/21),respectively.Conclusion 18 F-FDG SPECT image can be used as screening methods for detecting malignancies underlying iron deficiency anemia with fairly good accuracy.