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Oral epithelium as a surrogate tissue for assessing smoking-induced molecular alterations in the lungs.

CANCER PREVENTION RESEARCH, no. 1 (2008): 39-44

Cited: 83|Views31
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Abstract

The lungs and oral cavity of smokers are exposed to tobacco carcinogens. We hypothesized that tobacco-induced molecular alterations in the oral epithelium are similar to those in the lungs, and thus the oral epithelium may be used as a surrogate tissue for assessing alterations in the lungs. We used methylation-specific PCR to analyze pro...More

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